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A Fatal Inheritance
- How a Family Misfortune Revealed a Deadly Medical Mystery
- Narrated by: Roger Wayne
- Length: 9 hrs and 25 mins
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Publisher's summary
Weaving his own moving family story with a sweeping history of cancer research, Lawrence Ingrassia delivers an intimate, gripping tale that sits at the intersection of memoir and medical thriller
Ingrassia lost his mother, two sisters, brother, and nephew to cancer—different cancers developing at different points throughout their lives. And while highly unusual, his family is not the only one to wonder whether their heartbreak is the result of unbelievable bad luck, or if there might be another explanation.
Through meticulous research and riveting storytelling, Ingrassia takes us from the 1960s—when Dr. Frederick Pei Li and Dr. Joseph Fraumeni Jr. first met, not yet knowing that they would help make a groundbreaking discovery that would affect cancer patients for decades to come—to present day, as Ingrassia and countless others continue to unpack and build upon Li and Fraumeni’s initial discoveries, and to understand what this means for their families.
In the face of seemingly unbearable loss, Ingrassia holds onto hope. He urges us to “fight like Charlie,” his nephew who battled cancer his entire life starting with a rare tumor in his cheek at the age of two—and to look toward the future, as gene sequencing, screening protocols, CRISPR gene editing, and other developing technologies may continue to extend lifespans and perhaps, one day, even offer cures.
A Macmillan Audio production from Henry Holt & Company.
Critic reviews
“A Fatal Inheritance by Lawrence Ingrassia is a compelling personal chronicle of tragedy and triumph. It captures both the ineffable pain of families riddled with cancers and the remarkable research over the past half century by scientists determined to help them.”—Siddhartha Mukherjee, author of The Emperor of All Maladies: A Biography of Cancer
"When two young doctors came across a family riddled with cancer for generations, they wondered why and began a decades long search for the answer. In A Fatal Inheritance, a riveting narrative of their quest, Lawrence Ingrassia intertwines a deeply personal and tearful story of unbearable family loss with an inspiring story of scientific discovery that revolutionized the understanding and treatment of cancer."—Walter Isaacson, author of Elon Musk, The Code Breaker and Steve Jobs
"When Lawrence Ingrassia lost his mother, sisters, brother and nephew to cancer, was it appallingly bad luck, or was there a common cause? This is the story of a family tragedy, a medical mystery, and the painstaking work of insightful scientists. By turns heartbreaking and hopeful, A Fatal Inheritance is a story of mortal loss and human resilience."—Geraldine Brooks, author of Horse and March
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Inspiring story
- By Alicia on 05-08-24
By: Rae Wynn-Grant
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The Way You Make Me Feel
- Love in Black and Brown
- By: Nina Sharma
- Narrated by: Nina Sharma
- Length: 9 hrs and 21 mins
- Unabridged
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When Nina Sharma meets Quincy while hitching a ride to a friend’s Fourth of July barbecue, she spots a favorite book, Maxine Hong Kingston’s The Woman Warrior, in the back seat of his cramped car, and senses a sadness from him that’s all too familiar to her. She is immediately intrigued—who is this man? In The Way You Make Me Feel, Sharma chronicles her and Quincy’s love story, and in doing so, examines how their Black and Asian relationship becomes the lens through which she moves through and understands the world.
By: Nina Sharma
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Rednecks
- By: Taylor Brown
- Narrated by: Ramiz Monsef
- Length: 11 hrs and 25 mins
- Unabridged
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Award-winning novelist Taylor Brown brings to life one of the most compelling events in twentieth-century American history, reminding us of the hard-won origins of today’s unions. Rednecks is a propulsive, character-driven tale that’s both a century old and blisteringly contemporary: a story of unexpected friendship, heroism in the face of injustice, and the power of love and community against all odds.
By: Taylor Brown
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Fat Leonard
- How One Man Bribed, Bilked, and Seduced the U.S. Navy
- By: Craig Whitlock
- Narrated by: Dan Bittner
- Length: 11 hrs and 2 mins
- Unabridged
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Based on reams of confidential documents—including the blackmail files that Francis kept on Navy officers—Fat Leonard is the full, unvarnished story of a world-class con man and a captivating testament to the corrosive influence of greed within the ranks of the American military.
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Double standards
- By Patrick on 05-18-24
By: Craig Whitlock
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The Loves of Theodore Roosevelt
- The Women Who Created a President
- By: Edward F. O'Keefe
- Narrated by: Edward F. O'Keefe
- Length: 14 hrs and 36 mins
- Unabridged
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Theodore Roosevelt wrote in his senior thesis for Harvard in 1880 that women ought to be paid equal to men and have the option of keeping their maiden names upon marriage. It’s little surprise he’d be a feminist, given the women he grew up with. A dazzling and lyrical look at one America’s most significant presidents as we’ve never seen him before, The Loves of Theodore Roosevelt celebrates five extraordinary yet unsung women who opened the door to the American Century and pushed Theodore Roosevelt through it.
What listeners say about A Fatal Inheritance
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- A buyer
- 05-17-24
Powerful story told incredibly well
Cancer decimated the author's family, taking lives way too soon, way too often, as he recounts in this book. But this story is much bigger than that. It's an incredibly powerful tale, not just of his family, but of other families, of posing questions and seeking answers. The lyrical prose of his retelling reads like a novel, while his decades as a journalist with the Wall Street Journal, the New York Times, and the Los Angeles Times come through in his detailed chronicling of the journey to unwrap the medical mystery of why his branch of the family (and so many other families) have been plagued by cancer. He skillfully distills medical research into everyday language so that readers can understand the science, while he pieces in families' stories so that they can empathize with the real-life toll cancer takes on so many.
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